Products for Research Use Only

Cyclo (CLLFVY)

CAT: 0013-GTR19063699-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19063699-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cyclo (CLLFVY) is a cyclic peptide inhibitor of HIF-1 that targets the HIF-1α PAS-B domain, blocking dimerization and downstream gene expression (e.g., VEGF, CAIX) with IC50 values of 19 μM (U2OS) and 16 μM (MCF-7) . It is a research tool for studying hypoxia signaling and oncology in cellular models.
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Molecular Weight
738.94
Storage Conditions
-20°C
Notes
For research use only.