BI-78D3

• Description :

  BI-78D3 functions as a substrate competitive inhibitor of JNK, inhibit the JNK kinase activity (IC50=280 nM) .

• CAS Number :

  [883065-90-5]

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  JNK

• Type :

  Reference compound

• Related Pathways :

  MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Metabolic Disease; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/BI-78D3.html

• Purity :

  99.85

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1N(C2=CC=C(OCCO3)C3=C2)C(SC4=NC=C([N+]([O-])=O)S4)=NN1

• Molecular Formula :

  C13H9N5O5S2

• Molecular Weight :

  379.37

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Stebbins JL et al. Identification of a new JNK inhibitor targeting the JNK-JIP interaction site. Proc Natl Acad Sci U S A, 2008 Oct 28, 105 (43) :16809-13.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  JNK