STAT1 Luciferase Reporter-HeLa Cell Line
CAT:
519-RC1012
Size:
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 mL of 90% FBS + 10% DMSO.
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
STAT1 Luciferase Reporter-HeLa Cell Line
- Description: The STAT1 Luciferase Reporter cell line is a stably transfected HeLa cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the interferon (IFN) gamma activation sequence-based STAT1 response element, so that the cell line is designed to measure the transcriptional activity of STAT1. As a transcription factor, Signal Transducer and Activator of Transcription 1 (STAT1) is activated through phosphorylation at tyrosine 701 in response to various cytokines and growth factors such as IFN-alpha, IFN-gamma, IL-6, EGF and PDGF. The phosphorylated STAT1 forms homodimers or heterodimers with STAT3, and the dimers translocate to nucleus in which DNA binding/promoter induction occurs. The STAT1 induction by IFN-gamma is shown in Figure 1.
- Gene Name: STAT1
- Applications: Functional Assay
- Components: Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
- Storage Conditions: Immediately upon receipt, store in liquid nitrogen.
- Applications Notes: Functional Assay, detecting the transcriptional activity of STAT1