NFAT Luciferase Reporter-HEK293 Cell Line

• Description:

  The NFAT Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the Nuclear Factor of Activated T-cells (NFAT) response element, so that the cell line is designed to measure the transcriptional activity of NFAT. NFAT is a transcription factor originally found in activated T lymphocytes, and is now known to regulate not only T cell activation and differentiation but also the function of other immune cells including dendritic cells, B cells and megakaryocytes. The NFAT induction by calcium ionophore A23187 is shown in Figure 1.

• Gene Name:

  NFAT

• Applications:

  Functional Assay

• Dilution:

  Application: Culture conditions: Functional validation:

• Shipping Conditions:

  Available, requires dry ice shipping

• Storage Conditions:

  Immediately upon receipt, store in liquid nitrogen.

• Applications Notes:

  Functional Assay, detecting the transcriptional activity of NFAT