Anti-PR PGR Monoclonal Antibody

• Description:

  Boster Bio Anti-PR PGR Monoclonal Antibody catalog # M00541-2. Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3; PGR; NR3C3;

• Gene Name:

  PGR

• UniProt:

  P06401

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Clone:

  Clone: Z15

• Tissue Specificity:

  In reproductive tissues the expression of isoform A and isoform B varies as a consequence of developmental and hormonal status. Isoform A and isoform B are expressed in comparable levels in uterine glandular epithelium during the proliferative phase of the menstrual cycle. Expression of isoform B but not of isoform A persists in the glands during mid-secretory phase. In the stroma, isoform A is the predominant form throughout the cycle. Heterogeneous isoform expression between the glands of the endometrium basalis and functionalis is implying region- specific responses to hormonal stimuli.

• Applications:

  IF, IHC

• Purification:

  The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Function:

  The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor.

• Molecular Weight:

  98981 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  Progesterone receptor

• Subcellular Location:

  Nucleus. Cytoplasm. Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G (1) and G (2) /M phases.

• Protein Name:

  Progesterone receptor