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Anti-PTRF CAVIN1 Antibody

CAT: 0519-A31732-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A31732-1Size:100 µL
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Description
Boster Bio Anti-PTRF CAVIN1 Antibody catalog # A31732-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Caveolae-associated protein 1
Gene Name
CAVIN1
UniProt
Q6NZI2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human protein at AA range: 90-170
Clonality
Polyclonal
Applications
WB, ELISA
Purification
PTRF antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues (PubMed:18056712, PubMed:18191225, PubMed:19726876) . Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1) . Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop. Dissociates transcription complexes paused by DNA-bound TTF1, thereby releasing both RNA polymerase I and pre-RNA from the template (By similarity) .
Molecular Weight
43476 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Caveolae-associated protein 1
Subcellular Location
Membrane, caveola
Protein Name
Caveolae-associated protein 1

UniProtKB · Q6NZI2

Caveolae-associated protein 1

CAVN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6NZI2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CAVIN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2RAW7, O00535, Q6GMY1, Q96H74, Q9BT85, Q9HAP4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmEndoplasmic reticulumMembraneMicrosomeMitochondrionNucleus

Domain

Coiled coilRepeat

Disease

Congenital generalized lipodystrophyDiabetes mellitus

Molecular function

RNA-bindingrRNA-binding

Biological process

TranscriptionTranscription regulationTranscription termination

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A31732-2Anti-PTRF/CAVIN1 Antibody Picoband®
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GTR18539391PTRF/CAVIN1 Rabbit Polyclonal Antibody (HRP)
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