Anti-Importin subunit alpha-6 KPNA5 Antibody

Anti-Importin subunit alpha-6 KPNA5 Antibody

• Background: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA5 belongs to a subfamily within the KPNA family that also includes KPNA4 and 6 and is thought to be involved in NLS-dependent protein import into the nucleus.
• Description: Boster Bio Anti-Importin subunit alpha-6 KPNA5 Antibody (Catalog # A09441). Tested in ELISA, IHC-P applications. This antibody reacts with Human.
• Synonyms: SRP6, IPOA6, Importin subunit alpha-6, Karyopherin subunit alpha-5
• CAS Number: 9007-83-4
• Gene Name: KPNA5
• UniProt: O15131
• Host: Rabbit
• Reactivity: Human
• Cross Reactivity: KPNA5 antibody is human specific. KPNA5 antibody is predicted to not cross-react with other Importin alpha family members.
• Immunogen: KPNA5 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human KPNA5. The immunogen is located within amino acids 30 - 80 of KPNA5.
• Clonality: Polyclonal
• Applications: ELISA, IHC-P
• Purification: KPNA5 Antibody is affinity chromatography purified via peptide column.
• Concentration: 1 mg/mL
• Form: Liquid
• Molecular Weight: 60349 MW
• Components: KPNA5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Storage Conditions: KPNA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Fragment: IgG