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Human AREG Protein

CAT: 0749-PRP1075-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0749-PRP1075-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
AREG is a one-way membrane protein consisting of 252 amino acids. AREG belongs to AREG family and contains an EGF-like domain. AREG is expressed in many tissues, including ovary, placenta, lung, kidney, stomach, colon and breast. It is related to epidermal growth factor (EGF) and transforming growth factor α (TGF-α) .As an EGF-related growth factor, AREG interacts with EGF/TGF-α receptor to promote the growth of normal epithelial cells and inhibit the growth of some invasive cancer cell lines
Description
AREG is a one-way membrane protein consisting of 252 amino acids. AREG belongs to AREG family and contains an EGF-like domain. AREG is expressed in many tissues, including ovary, placenta, lung, kidney, stomach, colon and breast. It is related to epidermal growth factor (EGF) and transforming growth factor α (TGF-α) . As an EGF-related growth factor, AREG interacts with EGF/TGF-α receptor to promote the growth of normal epithelial cells and inhibit the growth of some invasive cancer cell lines.
Product Name Alternative
AR; SDGF; AREGB; CRDGF
Gene ID
374
Accession Number
P15514
Tag
AREG
Type
Cytokines and proteins
Applications
No tag
Purity
> 95 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Weight
11.4 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized recombinant Human AREG protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Protein Length
The recombinant Human AREG consists of 98 amino acids and predicts a molecular mass of 11.4 kDa.
Formulation
Lyophilized from sterile 20mM Tris, 800mM NaCl, pH 7.4.
Applications Notes
Human
Other Product Names
AR; SDGF; AREGB; CRDGF
Recommended Usage
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human AREG protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Preparation
E. coli
Accession Number URL
http://www.uniprot.org/uniprot/P15514
AA Sequence
Amino acid sequence derived from Human AREG (NC_000004.12) (Ser101-Lys198) was expressed.

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