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Chlorprothixene (Standard)

CAT: 0804-HY-B0274R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0274R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chlorprothixene (Standard) is the analytical standard of Chlorprothixene. This product is intended for research and analytical applications. Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity[1].
CAS Number
113-59-7
UNSPSC
12352005
Target
Bacterial; Dopamine Receptor; Histamine Receptor; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/chlorprothixene-standard.html
Solubility
H2O : < 0.1 mg/mL
Smiles
CN(C)CC/C=C1C2=C(SC3=C\1C=CC=C3)C=CC(Cl)=C2
Molecular Formula
C18H18ClNS
Molecular Weight
315.86
References & Citations
[1]Y von Coburg, et al. Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics. Bioorg Med Chem Lett. 2009 Jan 15;19 (2) :538-42.|[2]B L Roth, et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther. 1994 Mar;268 (3) :1403-10.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Launched

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