Products for Research Use Only
RegisterLogin

5-Iodouridine

CAT: 0804-HY-W011079-01Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W011079-01Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
5-Iodouridine is an iodine-containing pyrimidine nucleoside analog. 5-Iodouridine inhibits dihydroorotase with a Ki value of 340 µM. 5-Iodouridine significantly enhances the cell-killing effect of gamma irradiation. 5-Iodouridine can be used in the research of HSV-1 infection and leukemia[1][2][3].
CAS Number
1024-99-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/5-iodouridine.html
Purity
99.93
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO
Molecular Formula
C9H11IN2O6
Molecular Weight
370.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Bresnick E, et al. Inhibition of dihydroorotase by purines and pyrimidines. Biochimica et Biophysica Acta (BBA) -Specialized Section on Enzymological Subjects, 1964, 81 (1) : 150-157. |[2]Kuroda Y, et al. Radiosensitization of cultured mammalian cells by 5-iodouridine. Int J Radiat Biol Relat Stud Phys Chem Med. 1975 Mar;27 (3) :247-57.|[3]Kumar R, et al. Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine. J Med Chem. 1990 Feb;33 (2) :717-23.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W5537302’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine
HY-W003027-012-Bromo-5-iodopyridine
HY-W007531-012-Fluoro-5-iodopyridine
HY-W002858-012-Chloro-5-iodopyridine
HY-W002668-015-Bromo-2-iodopyridine
HY-160457-01FABP4/5-IN-5
HY-1494765-LOX-IN-5
HY-N85815,5'-Dimethoxysecoisolariciresinol
HY-N26485,5'-Dimethoxylariciresinol
HY-1543445′-Deoxy-5′-iodo-5-methyluridine

Alternative Products

CatalogName
436776-015-Iodouridine
TNU08865'-Deoxy-5'-iodouridine
BA4312-1005-Deoxy-5-iodouridine
ND144937-015’-Deoxy-5’-iodouridine
295733-012'-Deoxy-5-iodouridine
ND163032-012’,5’-Dideoxy-5’-iodouridine
GTR19214409-012',5'-Dideoxy-5'-iodouridine
NF77568-015-Fluoro-6-iodouridine
234247-015-Iodouridine 99+% (HPLC)
BUP158192'-O-Methyl-5-iodouridine

Popular Products