Recombinant Rat FGF-2/FGFb Protein

Recombinant Rat FGF-2/FGFb Protein

• Background: FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.
• Abbreviation: FGF-2;FGFb
• Synonyms: Basic Fibroblast Growth Factor, FGF-2, FGF2, FGFB, Fibroblast Growth Factor 2, HBGF-2, Heparin-Binding Growth Factor 2, bFGF
• CAS Number: 9000-83-3
• UniProt: P13109
• Accession Number: P13109
• Host: E. coli
• Origin Species: Rat
• Tag: None
• Sequence: Ala11-Ser154
• Applications: Cell culture
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.3-1. 8 ng/ml.
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 16 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.