Recombinant Mouse CD27 Ligand/TNFSF7/CD70 (N-10His)

Recombinant Mouse CD27 Ligand/TNFSF7/CD70 (N-10His)

• Background: CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
• Abbreviation: TNFSF7;CD70
• Synonyms: CD27 ligand, CD27L, CD27LG, CD70, CD70 antigen, TNFSF7, Tumor necrosis factor ligand superfamily member 7
• CAS Number: 9000-83-3
• UniProt: Q05A52
• Accession Number: Q05A52
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: N-His
• Sequence: Gln47-Pro195
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 25-30 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.