Recombinant Mouse CD27/TNFRSF7 Protein (Fc & His Tag)

Recombinant Mouse CD27/TNFRSF7 Protein (Fc & His Tag)

• Background: Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
• Abbreviation: CD27;TNFRSF7
• Synonyms: CD27 antigen, CD27L receptor, S152, T-cell activation antigen CD27, Tnfrsf7, Tp55, Tumor necrosis factor receptor superfamily member 7
• CAS Number: 9000-83-3
• Accession Number: P41272
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-Fc-His
• Sequence: Pro24-Arg182
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 50-70 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.