Recombinant Mouse Interleukin-36 gamma/IL-36 gamma/IL-1F9

Recombinant Mouse Interleukin-36 gamma/IL-36 gamma/IL-1F9

• Background: Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.
• Abbreviation: IL-36 gamma;IL-1F9
• Synonyms: Il1f, IL-1-related protein, Interleukin-1 homolog, IL-1F, IL-1H, IL-1RP, IL-1 epsilon, IL-1F9, IL-1H1, IL-1-related protein 2, IL-1RP2, Interleukin-1 homolog 1, Interleukin-36 gamma, Il1f9, Il36g, IL-17E
• CAS Number: 9000-83-3
• UniProt: Q8R460
• Accession Number: Q8R460
• Host: E. coli
• Origin Species: Mouse
• Tag: None
• Sequence: Gly13-Ser164
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 17 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.