Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His)

Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His)

• Background: NY-ESO-1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. Optimally assembled peptide-HLA-B2M trimer translocates to the surface of antigen-presenting cells, where it interacts with TCR and CD8 coreceptor on the surface of T cells.
• Abbreviation: HLA-A*0201 NY-ESO-1 complex
• Synonyms: HLA-A*0201 NY-ESO-1 complex Protein, MHC, MY-ESO-1
• CAS Number: 9000-83-3
• UniProt: P61769;P01892
• Accession Number: P61769&P01892
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-His
• Sequence: SLLMWITQC&Ile21-Met119&Gly25-Ile308(Ala269Val)
• Field of Research: Microbiology;immunology;Cardiovascular;Cancer
• Purity: > 90 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 55-60 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.