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Recombinant Human UBE2D3 Protein

CAT: 0763-PKSH033183-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0763-PKSH033183-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UBE2D3 is an enzyme that belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.
Abbreviation
UBE2D3
Synonyms
UBE2D3 and UBCH5C.; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2 D3; Ubiquitin-conjugating enzyme E2 (17) KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3
UniProt
P61077
Accession Number
AAH66917
Expression System
E.coli
Tag
None
Sequence
Met 1-Met 147
Field of Research
Cell biology; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
16.6 kDa
Observed Molecular Weight
15 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 150mM NaCl, 50% Glycerol, 0.05% Tween 80, 1mM TCEP, pH7.1.
Species
Human

UniProtKB · P61077

Ubiquitin-conjugating enzyme E2 D3

UB2D3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P61077
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
UBE2D3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.23
Processing
—
Secondary accessions
A6NJ93, A6NJB1, A6NM99, P47986, Q6IB88, Q6NXS4, Q8N924
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisDNA damageDNA repairUbl conjugation pathway

Cellular component

Cell membraneEndosomeMembrane

PTM

Disulfide bondPhosphoprotein

Molecular function

Transferase
Product Datasheet
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