Recombinant Human UBE2B/HR6B Protein

Recombinant Human UBE2B/HR6B Protein

• Background: Ubiquitin-Conjugating Enzyme E2 B (UBE2B) belongs to the ubiquitin-conjugating enzyme family. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins; and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth.Additionally; UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
• Abbreviation: UBE2B;HR6B
• Synonyms: HR6B, RAD6 Homolog B, RAD6B, UBE2B, Ubiquitin Carrier Protein B, Ubiquitin-Conjugating Enzyme E2 B, Ubiquitin-Conjugating Enzyme E2-17 kDa, Ubiquitin-Protein Ligase B, hHR6B
• CAS Number: 9000-83-3
• UniProt: P63146
• Accession Number: P63146
• Host: E. coli
• Origin Species: Human
• Tag: None
• Sequence: Met 1-Ser152
• Field of Research: Cell biology;Cancer;epigenetics and nuclear signal;metabolism
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Not Applicable
• Molecular Weight: 18 kDa
• Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
• Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.