Recombinant Human PDCD5/TFAR19 Protein (His Tag)

• Background:

  Programmed Cell Death Protein 5 (PDCD5) is a member of the PDCD5 family. PDCD5 is expressed in tumor cells during apoptosis, independent of apoptosis-inducing stimuli. This protein may function in the process of apoptosis. PDCD5 is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 may play an important regulator of K (lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. PDCD5 is an important novel protein that regulates both apoptotic and non-apoptotic programmed cell death.

• Abbreviation:

  PDCD5; TFAR19

• Synonyms:

  PDCD5; Programmed Cell Death Protein 5; Protein TFAR19; TF-1 Cell Apoptosis-Related Protein 19; TFAR19

• UniProt:

  O14737

• Accession Number:

  O14737

• Expression System:

  E.coli

• Tag:

  N-His

• Sequence:

  Met 1-Tyr125

• Field of Research:

  Cell biology; Cancer

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  16.4 kDa

• Observed Molecular Weight:

  20 kDa

• Species:

  Human