Recombinant Human SNU13 Protein (His Tag)

• Background:

  NHP2-Like Protein 1 (NHP2L1) is a member of the ribosomal protein L7Ae family. NHP2L1 proteinis limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 has been shown to interact with RAD17and PRPF31. The protein undergoes a conformational change upon RNA-binding. NHP2L1 binds to the 5-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly, prior to step I of splicing catalysis.

• Abbreviation:

  SNU13

• Synonyms:

  High Mobility Group-Like Nuclear Protein 2 Homolog 1; NHP2-Like Protein 1; NHP2L1; OTK27; SNU13 Homolog; U4/U6.U5 tri-snRNP 15.5 kDa Protein; hSNU13

• UniProt:

  P55769

• Accession Number:

  P55769

• Expression System:

  E.coli

• Tag:

  N-His

• Sequence:

  Met 1-Val128

• Field of Research:

  Epigenetics and nuclear signal

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  16.3 kDa

• Observed Molecular Weight:

  16 kDa

• Species:

  Human