Recombinant Human FGF-7/KGF Protein

• Background:

  Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities; and are involved in a variety of biological processes; including embryonic development; cell growth; morphogenesis; tissue repair; tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor; whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.

• Abbreviation:

  FGF-7; KGF

• Synonyms:

  FGF-7; FGF7; Fibroblast growth factor 7; HBGF-7; Heparin-binding growth factor 7; KGF; Keratinocyte growth factor

• UniProt:

  P21781

• Accession Number:

  P21781

• Expression System:

  E.coli

• Tag:

  None

• Sequence:

  Cys32-Thr194

• Field of Research:

  Signal Transduction; Cancer

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  18.9 kDa

• Observed Molecular Weight:

  17 kDa

• Species:

  Human