Recombinant Human FGF-2/FGFb Protein
CAT:
763-PKSH032438-01
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human FGF-2/FGFb Protein
- Background: Fibroblast growth factor 2(FGF2) is a secreted protein and belongs to the heparin-binding growth factors family. FGF2 is produced by epithelial; tumor and other cell types. It involved in developmental processes and regulates differentiation; proliferation; and migration; FGF2 is a critical factor for growing embryonic stem cells in culture without inducing differentiation. FGF2 has a high affinity for heparan sulfate and binding is a step in the FGF basic activation of FGFR tyrosine kinase.
- Abbreviation: FGF-2;FGFb
- Synonyms: Basic fibroblast growth factor, Bfgf, FGF-2, FGF2, FGFB, Fibroblast growth factor 2, HBGF-2, Heparin-binding growth factor 2
- UniProt: P09038
- Accession Number: P09038
- Host: E. coli
- Origin Species: Human
- Tag: N-His
- Sequence: Ala 135-Ser 288
- Applications: Cell culture
- Field of Research: Signal Transduction;Cardiovascular;Neuroscience;Cancer;Developmental Biology;Stem cells
- Purity: > 98 % as determined by reducing SDS-PAGE.
- Bioactivity: Measure by its ability to induce 3T3 cells proliferation. The ED50 for this effect is <1 ng/mL. The specific activity of recombinant human FGF-2 is approximately >5 x 105 IU/mg.
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 17 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.