Recombinant Human FGF-17 Protein

• Background:

  Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding growth factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth; morphogenesis; tissue repair; tumor growth; and invasion. FGF17 plays an important role in the regulation of embryonic development and it acts as signaling molecule in the induction and patterning of the embryonic brain. In addition; FGF17 stimulates the proliferation and activation of cells that express FGF receptors.

• Abbreviation:

  FGF-17

• Synonyms:

  FGF-17; FGF17; Fibroblast Growth Factor 17

• UniProt:

  O60258

• Accession Number:

  O60258

• Expression System:

  E.coli

• Tag:

  N-His

• Sequence:

  Thr 23-Thr 216

• Applications:

  Cell culture

• Field of Research:

  Signal Transduction; Cardiovascular; Cancer

• Endotoxin:

  < 0.1 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 98 % as determined by reducing SDS-PAGE.

• Bioactivity:

  50 2 x 105 IU/mg.5

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  23.3 kDa

• Observed Molecular Weight:

  24 kDa

• Species:

  Human