Recombinant Human CXCL12/SDF-1 Protein (aa22-89)

Recombinant Human CXCL12/SDF-1 Protein (aa22-89)

• Background: Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1α and SDF1β are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface; and can also bind syndecan4. SDF1 is known to influence lymphopoiesis; regulate patterning and cell number of neural progenitors; and promote angiogenesis. It also enhances the survival of myeloid progenitor cells.
• Abbreviation: CXCL12;SDF-1
• Synonyms: C-X-C Motif Chemokine 12, CXCL12, IRH, Intercrine Reduced in Hepatomas, PBSF, Pre-B Cell Growth-Stimulating Factor, SDF-1, SDF1, SDF1A, SDF1B, Stromal Cell-Derived Factor 1, hIRH, hSDF-1
• CAS Number: 9000-83-3
• UniProt: P48061
• Accession Number: P48061
• Host: E. coli
• Origin Species: Human
• Tag: None
• Sequence: Lys22-Lys89
• Field of Research: Microbiology;Cardiovascular;immunology
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 10 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.