Recombinant Human CXCL12/SDF-1 Protein (aa19-93)

• Background:

  Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1α and SDF1β are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface; and can also bind syndecan4. SDF1 is known to influence lymphopoiesis; regulate patterning and cell number of neural progenitors; and promote angiogenesis. It also enhances the survival of myeloid progenitor cells.

• Abbreviation:

  CXCL12; SDF-1

• Synonyms:

  C-X-C Motif Chemokine 12; CXCL12; IRH; Intercrine Reduced in Hepatomas; PBSF; Pre-B Cell Growth-Stimulating Factor; SDF-1; SDF1; SDF1A; SDF1B; Stromal Cell-Derived Factor 1; hIRH; hSDF-1

• UniProt:

  P48061

• Accession Number:

  P48061

• Expression System:

  E.coli

• Tag:

  None

• Sequence:

  Ser19-Met93

• Field of Research:

  Microbiology; Cardiovascular; immunology

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  8.8 kDa

• Observed Molecular Weight:

  12 kDa

• Species:

  Human