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LY 186126

CAT: 0804-HY-109992Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-109992Size:1 Each
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Description
LY 186126 a Indolidan analog, is a phosphodiesterase (PDE) inhibitor. LY 186126 binds to cardiac sarcoplasmic reticulum PDE with high affinity, with a Kd of 5.6 nM[1].
CAS Number
100644-00-6
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ly-186126.html
Smiles
O=C1N(C)C2=C(C=C(C(C(C)C3)=NNC3=O)C=C2)C1(C)C
Molecular Formula
C16H19N3O2
Molecular Weight
285.34
References & Citations
[1]T Ashikaga, et al. Comparison of indolidan analog binding sites of drug antibody and sarcoplasmic reticulum with inhibition of cyclic AMP phosphodiesterase. J Recept Signal Transduct Res. 1996 Sep-Nov;16 (5-6) :315-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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