Recombinant Cyclin E2 Monoclonal Antibody

• Background:

  The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition.

• Abbreviation:

  Cyclin E2

• UniProt:

  O96020

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide of human Cyclin E2

• Target:

  CCNE2; CYCE2; cyclin E2

• Clonality:

  Monoclonal

• Clone:

  R02-1C0

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC-P; IF

• Field of Research:

  Cancer; Cell Biology; Epigenetics and Nuclear Signaling

• Purification:

  Affinity Purified

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:500-1:1000; IHC 1:50-1:100; IF 1:20-1:100

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  47kDa

• Observed Molecular Weight:

  47kDa

• Isotype:

  IgG