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GRIN1 Polyclonal Antibody

CAT: 0763-E-AB-70244-02Size: 120 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-70244-02Size:120 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
Abbreviation
GRIN1
UniProt
P35438
Host
Rabbit
Reactivity
Mouse
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse NMDAR1
Target
GluN1; Glutamate [NMDA] receptor subunit zeta-1; Glutamate receptor ionotropic N methyl D aspartate 1; Glutamate receptor ionotropic; N-methyl-D aspartate; subunit 1; glutamate receptor ionotropic; NMDA 1; Grin1; MRD8; N methyl D aspartate receptor; N methyl D aspartate receptor channel subunit zeta 1; N methyl D aspartate receptor subunit NR1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; NMDA 1; NMDA R1; NMDA receptor 1; NMDA1; NMDAR; NMDZ1; NR1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Neuroscience
Purification
Affinity purification
Concentration
480 μg/mL
Dilution
IHC 1:100-1:500
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P35438

Glutamate receptor ionotropic, NMDA 1

NMDZ1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P35438
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Grin1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
GluN1
EC number
—
Processing
Precursor
Secondary accessions
A2AI15, A2AI18, Q8CFS4
Protein keywords

Technical term

3D-structureReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMagnesiumMetal-bindingZinc

Cellular component

Cell membraneMembranePostsynaptic cell membraneSynapse

PTM

Disulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

Ion channelLigand-gated ion channelReceptor

Biological process

Ion transportTransport

Domain

SignalTransmembraneTransmembrane helix
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