SIRT3 Polyclonal Antibody

CAT: 0763-E-AB-70222-01Size: 60 µLDry Ice: NoHazardous: No

1 / 1

CAT#:0763-E-AB-70222-01Size:60 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Abbreviation

SIRT3

UniProt

Q8R104

Host

Rabbit

Reactivity

Mouse

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse SIRT3

Target

HSIRT 3; hSIRT3; Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase; NAD dependent deacetylase sirtuin 3 mitochondrial; NAD-dependent protein deacetylase sirtuin-3; mitochondrial; Regulatory protein SIR2 homolog 3; Silent mating type information regulation 2 S.cerevisiae homolog 3; Sir 2 like 3; SIR 2 like protein 3; SIR 3; SIR2 L3; Sir2 like 3; SIR2 like protein 3; SIR2-like protein 3; SIR2L3; SIR3; SIRT 3; SIRT3; Sirtuin 3; Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae) ; Sirtuin type 3; Sirtuin3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Cancer; Cell Biology; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism

Purification

Affinity purification

Concentration

500 μg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

28kDa

Observed Molecular Weight

28kDa

Isotype

IgG

UniProtKB · Q8R104

NAD-dependent protein deacetylase sirtuin-3

SIR3_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: Q8R104
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Sirt3
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: —
EC number: 2.3.1.286
Processing: Precursor
Secondary accessions: B9W0A9, C6ZII7, Q9EPA8

Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmMitochondrion

Ligand

Metal-bindingNADZinc

Technical term

Reference proteome

Molecular function

Transferase

Domain

Transit peptide

Product Datasheet

Related Products

Catalog	Name
AN300974L-01	Recombinant SIRT3 Monoclonal Antibody
PDEH101116-01	Recombinant Human SIRT3 Protein (Sumo Tag)
E-AB-70223-01	SIRT7 Polyclonal Antibody
E-AB-64253-01	SIRT2 Polyclonal Antibody
E-AB-60061-01	SIRT2 Polyclonal Antibody
E-AB-32901-01	SIRT1 Polyclonal Antibody
E-AB-16821-01	SIRT4 Polyclonal Antibody
E-AB-67101-01	SIRT1 Polyclonal Antibody
E-AB-70368-01	SIRT1 Polyclonal Antibody
E-AB-60124-01	SIRT7 Polyclonal Antibody

Alternative Products

Catalog	Name
MBS8572604-01	SIRT3 Polyclonal Antibody
BS80303	SIRT3 polyclonal antibody