Products for Research Use Only

C-Myc Polyclonal Antibody

CAT: 0763-E-AB-68295-01Size: 60 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0763-E-AB-68295-01Size:60 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Abbreviation
C-Myc
UniProt
P01106
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
A synthetic peptide of human c-Myc
Target
MRTL; MYCC; bHLHe39; c-Myc; MYC
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Stem Cells
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48kDa/50kDa
Observed Molecular Weight
60KDa
Isotype
IgG