PER1 Polyclonal Antibody

• Background :

  This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.

• Abbreviation :

  PER1

• UniProt :

  O15534

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Recombinant fusion protein of human PER1 (NP_002607.2) .

• Target :

  PER1; PER; RIGUI; hPER

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC; IF

• Field of Research :

  Epigenetics and Nuclear Signaling; Neuroscience

• Purification :

  Affinity purification

• Concentration :

  1mg/mL

• Dilution :

  IHC 1:50-1:100; IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG