PER3 Polyclonal Antibody

• Background:

  This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  PER3

• UniProt:

  P56645

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Fusion protein of human PER3

• Target:

  2810049O06Rik ; Cell growth inhibiting gene 13 protein; Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3; GIG13; gPER3; Growth inhibiting protein 13; HGNC:8847; hPER3; mPer3; Per3; PER3; Period 3; Period circadian clock 3; Period circadian protein 3; Period circadian protein homolog 3; Period homolog 3 (Drosophila) ; Period homolog 3; Period homolog 3; Drosophila; Period3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Cardiovascular; Epigenetics and Nuclear Signaling

• Purification:

  Antigen affinity purification

• Concentration:

  0.96 mg/mL

• Dilution:

  IHC 1:50-1:300

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG