CD3D Polyclonal Antibody

• Background:

  The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK) . Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

• Abbreviation:

  CD3D

• UniProt:

  P04234

• Host:

  Rabbit

• Reactivity:

  Human; Rat

• Immunogen:

  Recombinant fusion protein of human CD3D (NP_000723.1) .

• Target:

  CD3D; CD3-DELTA; IMD19; T3D

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC; IF

• Field of Research:

  Cancer; Immunology; Stem Cells

• Purification:

  Affinity purification

• Concentration:

  1mg/mL

• Dilution:

  IHC 1:50-1:100; IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG