Bcl-2 Polyclonal Antibody

• Background:

  This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

• Abbreviation:

  Bcl-2

• UniProt:

  P10415

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  A synthetic peptide of human Bcl-2

• Target:

  Bcl-2; PPP1R50; BCL2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC; IF

• Field of Research:

  Cancer; Cell Biology; Metabolism; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:50-1:100; IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  22kDa/26kDa

• Observed Molecular Weight:

  24kDa/26kDa

• Citation 01:

  https://www.mdpi.com/1806946

• Citation 02:

  https://www.mdpi.com/1281194

• Citation 03:

  https://link.springer.com/article/10.1007/s11356-023-26018-0

• Citation 04:

  https://onlinelibrary.wiley.com/doi/abs/10.1111/jre.12973

• Citation 05:

  https://www.sciencedirect.com/science/article/pii/S0300483X18303937

• Citation 06:

  https://www.mdpi.com/2080828

• Citation 07:

  https://www.sciencedirect.com/science/article/pii/S0006291X19321874

• Citation 08:

  https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-019-2768-1

• Citation 09:

  https://link.springer.com/article/10.1007/s12011-018-1587-4

• Isotype:

  IgG