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Bcl-2 Polyclonal Antibody

CAT: 0763-E-AB-60012-01Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-60012-01Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Abbreviation
Bcl-2
UniProt
P10415
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human Bcl-2
Target
Bcl-2; PPP1R50; BCL2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Cell Biology; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:100; IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22kDa/26kDa
Observed Molecular Weight
24kDa/26kDa
Citation 01
https://www.mdpi.com/1806946
Citation 02
https://www.mdpi.com/1281194
Citation 03
https://link.springer.com/article/10.1007/s11356-023-26018-0
Citation 04
https://onlinelibrary.wiley.com/doi/abs/10.1111/jre.12973
Citation 05
https://www.sciencedirect.com/science/article/pii/S0300483X18303937
Citation 06
https://www.mdpi.com/2080828
Citation 07
https://www.sciencedirect.com/science/article/pii/S0006291X19321874
Citation 08
https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-019-2768-1
Citation 09
https://link.springer.com/article/10.1007/s12011-018-1587-4
Isotype
IgG

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