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ITGB1BP1 Polyclonal Antibody

CAT: 0763-E-AB-53077-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-53077-01Size:20 µL
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Background
The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.
Abbreviation
ITGB1BP1
UniProt
O14713
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human ITGB1BP1
Target
Bodenin; DKFZp686K08158; ICAP 1; ICAP 1A; ICAP 1alpha; ICAP 1B; ICAP-1; ICAP-1A; ICAP-1alpha; ICAP-1B; ICAP1; ICAP1A; ICAP1B; Integrin beta 1 binding protein 1; Integrin beta-1-binding protein 1; Integrin cytoplasmic domain associated protein 1 alpha; Integrin cytoplasmic domain associated protein 1; Integrin cytoplasmic domain associated protein 1 beta; Integrin cytoplasmic domain-associated protein 1; ITBP1; ITGB1BP1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal transduction
Purification
Antigen affinity purification
Concentration
1.02 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · O14713

Integrin beta-1-binding protein 1

ITBP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14713
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGB1BP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D6W4Y9, O14714, Q53RS0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AngiogenesisBiomineralizationCell adhesionDifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Cellular component

Cell membraneCell projectionCytoplasmCytoskeletonMembraneNucleus

Molecular function

Mitogen

PTM

Phosphoprotein

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