TIMM8A Polyclonal Antibody

• Background :

  This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• Abbreviation :

  TIMM8A

• UniProt :

  O60220

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Fusion protein of human TIMM8A

• Target :

  DDP 1; DDP; DDP1; Deafness dystonia protein 1; Deafness/dystonia peptide; DFN 1; DFN1; MGC12262; Mitochondrial import inner membrane translocase subunit Tim8 A; MTS; TIM 8A; TIM8; TIM8A; TIM8A; TIMM 8A; timm8a; Translocase of inner mitochondrial membrane 8 homolog A; X linked deafness dystonia protein; X-linked deafness dystonia protein

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Neuroscience; Signal transduction

• Purification :

  Antigen affinity purification

• Concentration :

  1.62 mg/mL

• Dilution :

  IHC 1:50-1:300

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG