TIMM8A Polyclonal Antibody

• Background :

  This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• Description :

  This is a TIMM8A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  DDP 1, DDP, DDP1, Deafness dystonia protein 1, Deafness/dystonia peptide, DFN 1, DFN1, MGC12262, Mitochondrial import inner membrane translocase subunit Tim8 A, MTS, TIM 8A, TIM8, TIM8A, TIM8A, TIMM 8A, timm8a, Translocase of inner mitochondrial membrane 8 homolog A, X li

• Swiss Prot :

  O60220

• Accession Number :

  BC006994

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Fusion protein of human TIMM8A

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  1.62 mg/mL

• Dilution :

  IHC 1:50-1:300, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG