Products for Research Use Only
RegisterLogin

GSK3 alpha/beta Polyclonal Antibody

CAT: 0763-E-AB-31628-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0763-E-AB-31628-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin. GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3 kinase/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3βGSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus and mammalian development. GSK-3 has been shown to regulate cyclin D1 proteolysis and subcellular localization.
Abbreviation
GSK3α/β
UniProt
P49840, P49841
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human GSK3α/β around the non-phosphorylation site of Tyr279/216.
Target
GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
51kDa
Observed Molecular Weight
51,46kDa
Citation 01
https://www.frontiersin.org/articles/10.3389/fonc.2019.01469/full
Isotype
IgG

Related Products

CatalogName
E-AB-70043-01GSK3 beta Polyclonal Antibody
E-AB-31629-01GSK3 beta Polyclonal Antibody
E-AB-12494-01GSK3 alpha Polyclonal Antibody
E-AB-15704-01GSK3 alpha Polyclonal Antibody
E-AB-20886-01Phospho-GSK3 beta (Ser9) Polyclonal Antibody
E-AB-22130-01GSK3 beta Monoclonal Antibody
E-AB-22220-01GSK3 beta Monoclonal Antibody
E-AB-22221-01GSK3 beta Monoclonal Antibody
E-AB-81450-01Recombinant GSK3 beta Monoclonal Antibody
AN303202L-01Recombinant GSK3 beta Monoclonal Antibody

Alternative Products

CatalogName
BT-AP03847-01GSK3 Alpha/Beta Polyclonal Antibody
bs-7332RGSK3 Alpha + Beta Polyclonal Antibody
RC-6953-01Recombinant GSK3 alpha/GSK3 beta Antibody
70R-30578GSK3 alpha/beta antibody
DF6806-01GSK3 alpha/ beta Antibody
GWB-52E33BGSK3 alpha & beta Antibody
abx009185-01GSK3 alpha / beta Antibody
GTR17743885-01GSK3 Alpha + Beta Rabbit Polyclonal Antibody
400815-01GSK3 alpha/beta

Popular Products