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Claudin 4 Polyclonal Antibody

CAT: 0763-E-AB-30945-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-30945-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins. This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Abbreviation
Claudin-4
UniProt
O14493
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human Claudin-4
Target
Claudin-4; Claudin4; CLD4; CLDN 4; CLDN4; Clostridium perfringens enterotoxin receptor 1; Clostridium perfringens enterotoxin receptor; CPE R; CPE receptor; CPE-R; CPE-receptor; CPER; CPETR 1; CPETR; CPETR1; hCPE R; WBSCR8; Williams Beuren syndrome chromosome region 8 protein; Williams-Beuren syndrome chromosomal region 8 protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Signal Transduction
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22kDa
Observed Molecular Weight
22kDa
Isotype
IgG

UniProtKB · O14493

Claudin-4

CLD4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14493
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CLDN4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell junctionCell membraneMembraneTight junction

Ligand

Chloride

Molecular function

Chloride channelIon channel

PTM

Disulfide bondPhosphoprotein

Biological process

Ion transportTransport

Domain

TransmembraneTransmembrane helix

Disease

Williams-Beuren syndrome

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