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GALR1 Polyclonal Antibody

CAT: 0763-E-AB-19892-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19892-01Size:20 µL
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Background
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
Abbreviation
GALR1
UniProt
P47211
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human GALR1
Target
Gal receptor 1; gal-1 receptor; GAL1R; galanin receptor 1; galanin receptor 1; brain; Galanin receptor; Galanin receptor type 1; galanin-1 receptor; GALNR; GALNR1; GALR1; hugal 1-r
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cardiovascular; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
1.8 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P47211

Galanin receptor type 1

GALR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P47211
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GALR1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GAL1-R, GALR-1
EC number
—
Processing
—
Secondary accessions
Q4VBL7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinLipoproteinPalmitate

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

TransmembraneTransmembrane helix