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C14orf2 Polyclonal Antibody

CAT: 0763-E-AB-19636-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19636-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
C14orf2, also known as MP68, MP68 is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD) . The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
Abbreviation
C14orf2
UniProt
P56378
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human C14orf2
Target
6.8 kDa mitochondrial proteolipid;68MP; Chromosome 14 open reading frame 2; MP68; PLPM
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology
Purification
Antigen affinity purification
Concentration
1.1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
7 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · P56378

ATP synthase F(0) complex subunit j, mitochondrial

ATP68_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P56378
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ATP5MJ
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R588, G3V5Q3, Q86TT7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

MembraneMitochondrion

Domain

TransmembraneTransmembrane helix

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