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GKN1 Polyclonal Antibody

CAT: 0763-E-AB-19492-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19492-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gastrokine 1 (GKN1), a stomach-specic protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin, belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach, but is absent from gastric adenocarcinomas, gastro-esophageal adenocarcinoma cell lines, and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.
Abbreviation
GKN1
UniProt
Q9NS71
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human GKN1
Target
18 kDa antrum mucosa protein; AMP 18; AMP-18; AMP18; Antrum mucosa protein;18-KD; BRICD 1; BRICD1; BRICHOS domain containing 1; CA 11; CA11; CA11 gene; CA11 protein; FOV; Foveolin; Gastrokine-1; Gastrokine1; GKN 1; Gkn1; GKN1; MGC70354; Protein CA11; UNQ489/PRO1005
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Tags and Cell Markers
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · Q9NS71

Gastrokine-1

GKN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NS71
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GKN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q8IUA9
Protein keywords

PTM

Disulfide bond

Cellular component

Golgi apparatusSecreted

Molecular function

Mitogen

Technical term

Proteomics identificationReference proteome

Domain

Signal

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