BAG2 Polyclonal Antibody

• Background:

  BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

• Abbreviation:

  BAG2

• UniProt:

  O95816

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human BAG2

• Target:

  BAG 2; BAG family molecular chaperone regulator 2; BAG-2; BAG-family molecular chaperone regulator-2; Bag2; BAG2; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; BCL2-associated athanogene 2; dJ417I1.2 (BAG family molecular chaperone regulator 2) ; dJ417I1.2; KIAA0576; MGC149462; OTTHUMP00000016668

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cell Biology; Signal Transduction; Cancer; Metabolism

• Purification:

  Antigen affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:30-1:150

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  24 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG