BAG3 Polyclonal Antibody

• Background:

  Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

• Abbreviation:

  BAG3

• UniProt:

  O95817

• Host:

  Rabbit

• Reactivity:

  Human; Rat

• Immunogen:

  Recombinant Human BAG3 protein expressed by E.coli

• Target:

  BAG family molecular chaperone regulator 3 ; BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BIS

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Cell Biology; Metabolism

• Purification:

  Antigen Affinity Purification

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  62 kDa

• Observed Molecular Weight:

  80 kDa

• Isotype:

  IgG