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PLCB2 Polyclonal Antibody

CAT: 0763-E-AB-19161-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19161-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
Abbreviation
PLCB2
UniProt
Q00722
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human PLCB2
Target
1-phosphatidylinositol-4;1-phosphatidylinositol-4;5-bisphosphate phosphodiesterase beta-2;5-bisphosphate phosphodiesterase beta-2; FLJ38135; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2; Plcb2; PLCB2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Metabolism; Signal transduction
Purification
Antigen affinity purification
Concentration
1.02 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q00722

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

PLCB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q00722
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PLCB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.4.11
Processing
—
Secondary accessions
A8K6J2, B9EGH5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMetal-binding

Domain

Coiled coil

Molecular function

HydrolaseTransducer

Biological process

Lipid degradationLipid metabolism

PTM

Phosphoprotein