MTHFS Polyclonal Antibody

• Background:

  The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.

• Abbreviation:

  MTHFS

• UniProt:

  P49914

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Fusion protein of human MTHFS

• Target:

  10-methenyl-tetrahydrofolate synthetase;5 10 methenyl tetrahydrofolate synthetase;5;5 formyltetrahydrofolate cyclo ligase;5;10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) ;5-formyltetrahydrofolate cyclo-ligase; FLJ30410; HsT19268; Methenyl THF synthetase; Methenyl-THF synthetase; MTHFS; MTHFS

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Metabolism; Signal transduction

• Purification:

  Antigen affinity purification

• Concentration:

  0.78 mg/mL

• Dilution:

  IHC 1:40-1:200

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG