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POMGNT1 Polyclonal Antibody

CAT: 0763-E-AB-18855-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-18855-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described.
Abbreviation
POMGNT1
UniProt
Q8WZA1
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human POMGNT1
Target
2-N-acetylglucosaminyltransferase 1;2-N-acetylglucosaminyltransferase I.2; GnT I.2; GnTI.2; MEB; MGAT 1.2; MGAT1.2; O linked mannose beta1 2 N acetylglucosaminyltransferase; PMGT1; POMGNT 1; POMGnT1; Protein O linked mannose beta 1 2 N acetylglucosaminyltransferase 1; Protein O linked mannose beta1 2 N acetylglucosaminyltransferase; Protein O-linked-mannose beta-1; UDP GlcNAc; UDP GlcNAc:alpha D mannoside beta 1 2 N acetylglucosaminyltransferase I.2; UDP-GlcNAc:alpha-D-mannoside beta-1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Tags; Cell Markers
Purification
Antigen affinity purification
Concentration
0.96 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
75 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · Q8WZA1

Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

PMGT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WZA1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POMGNT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
POMGnT1
EC number
2.4.1.-
Processing
—
Secondary accessions
D3DQ16, Q5VST2, Q5VST3, Q9BV55, Q9H9L8, Q9NXF9, Q9NYF7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Congenital muscular dystrophyDisease variantDystroglycanopathyLimb-girdle muscular dystrophyLissencephalyRetinitis pigmentosa

PTM

Disulfide bondPhosphoprotein

Molecular function

GlycosyltransferaseTransferase

Cellular component

Golgi apparatusMembrane

Ligand

LectinManganeseMetal-binding

Domain

Signal-anchorTransmembraneTransmembrane helix

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