MGP Polyclonal Antibody

CAT: 0763-E-AB-18763-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-18763-01Size:20 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Matrix Gla protein (MGP) is is a vitamin K-dependent, extracellular matrix protein. MGP plays a pivotal role in preventing soft tissue calcification and local mineralization of the vascular wall. Vitamin K deficiency leads to inactive uncarboxylated MGP (ucMGP), which accumulates at sites of arterial calcification. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. Defects in MGP are the cause of Keutel syndrome (KS), which is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.
Abbreviation
MGP
UniProt
P08493
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human MGP
Target
Cell growth inhibiting gene 36 protein; Cell growth-inhibiting gene 36 protein; GAMMA-CARBOXYGLUTAMIC ACID PROTEIN; MATRIX; GIG36; Matrix Gla protein; MGLAP; MGP; MGP; NTI
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Antigen affinity purification
Concentration
1.32 mg/mL
Dilution
IHC 1:70-1:350
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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