HMBS Polyclonal Antibody

• Background:

  This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

• Abbreviation:

  HMBS

• UniProt:

  P08397

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Fusion protein of human HMBS

• Target:

  HEM3; HMBS; Hydroxymethylbilane synthase; PBG D; PBG-D; PBGD; PORC; Porphobilinogen deaminase; porphyria; acute; Chester type; Pre uroporphyrinogen synthase; Pre-uroporphyrinogen synthase; UPS; Uroporphyrinogen I synthase; Uroporphyrinogen I synthetase

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Cell Biology; Metabolism; Signal Transduction

• Purification:

  Antigen affinity purification

• Concentration:

  1.08 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  39 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG