IDO2 Polyclonal Antibody

• Background :

  INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

• Abbreviation :

  IDO2

• UniProt :

  Q6ZQW0

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Full length fusion protein

• Target :

  3-dioxygenase 2;3-dioxygenase-like protein 1; EC 1.13.11.; I23O2; IDO 2; IDO-2; Ido2; INDOL 1; Indoleamine 2; Indoleamine 2;3 dioxygenase 2; Indoleamine 2;3 dioxygenase like 1 protein; Indoleamine 2;3 dioxygenase like protein 1; Indoleamine pyrrole 2;3 dioxygenase like 1; Indoleamine pyrrole 2;3 dioxygenase like protein 1; Indoleamine-pyrrole 2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Metabolism; Signal Transduction

• Purification :

  Antigen affinity purification

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000; IHC 1:30-1:150

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  45 kDa

• Observed Molecular Weight :

  Refer to figures

• Isotype :

  IgG