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WWP1 Polyclonal Antibody

CAT: 0763-E-AB-18315-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-18315-01Size:20 µL
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Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes.
Abbreviation
WWP1
UniProt
Q9H0M0
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human WWP1
Target
AIP 5; AIP5 ; Atropin-1-interacting protein 5; hSDRP1; Nedd 4 like ubiquitin protein ligase; nedd4 like; NEDD4-like E3 ubiquitin-protein ligase WWP1; TGIF interacting ubiquitin ligase 1; Tiul1; WW domain containing E3 ubiquitin protein ligase 1; WW domain-containing protein 1; WWP 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology
Purification
Antigen affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
105 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · Q9H0M0

NEDD4-like E3 ubiquitin-protein ligase WWP1

WWP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H0M0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WWP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.26
Processing
—
Secondary accessions
O00307, Q5YLC1, Q96BP4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneCytoplasmMembraneNucleus

Biological process

Host-virus interactionUbl conjugation pathway

Domain

Repeat

Molecular function

Transferase

PTM

Ubl conjugation